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Diabetes is a disease in which blood glucose levels are above normal. People with diabetes have problems converting food to energy. After a meal, food is broken down into a sugar called glucose, which is carried by the blood to cells throughout the body. Cells use the hormone insulin, made in the pancreas, to help them process blood glucose into energy.
The three main kinds of diabetes are type 1, type 2, and gestational diabetes.
or juvenile diabetes, is a form of diabetes in which the beta cells of the pancreas no longer make insulin because the body's immune system has attacked and destroyed them.
is caused by the hormones of pregnancy or a shortage of insulin. Gestational diabetes usually goes away after the baby is born.
is the most common form of diabetes. People who are overweight and inactive are more likely to develop type 2 diabetes. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. Over the years, high blood glucose damages nerves and blood vessels, leading to complications such as heart disease, stroke, blindness, kidney disease, nerve problems, gum infections, and amputation.
More than 6 million people in the United States have type 2 diabetes and do not know it. Many have no signs or symptoms; others have symptoms but do not suspect diabetes. Symptoms include:
The following tests are used for diagnosis:
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